SCHEMBL1033281

SCHEMBL1033281

O=C(O)C=CCCCCCCCCNCC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 9/20 0.42
PPARG P37231 2/20 0.42
PPARA Q07869 2/20 0.42
TBXAS1 P24557 2/20 0.41
GMNN O75496 1/20 0.40
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX15 P16050 1/20 0.40
APEX1 P27695 1/20 0.40
CYP2C19 P33261 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HSD17B10 Q99714 1/20 0.40
DUSP3 P51452 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4391717 0.82 EPHX2 (0.47) EPHX2PPARGPPARAGMNNUSP2
SCHEMBL7856919 0.81 PTPN1 (0.52) PPARGPPARATBXAS1GMNNUSP2
SCHEMBL7856303 0.81 PTPN1 (0.52) PPARGPPARATBXAS1GMNNUSP2
SCHEMBL7856305 0.81 PTPN1 (0.52) PPARGPPARATBXAS1GMNNUSP2
SCHEMBL18045567 0.81 MAOA (0.50) EPHX2LMNA
SCHEMBL7856285 0.81 PTPN1 (0.52) PPARGPPARATBXAS1GMNNUSP2
SCHEMBL10017358 0.81 PTPN1 (0.52) PPARGPPARATBXAS1GMNNUSP2
SCHEMBL1815001 0.81 PTPN1 (0.52) PPARGPPARATBXAS1GMNNUSP2
SCHEMBL7856296 0.81 PTPN1 (0.52) PPARGPPARATBXAS1GMNNUSP2
SCHEMBL7856294 0.81 PTPN1 (0.52) PPARGPPARATBXAS1GMNNUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8287846-B2 Cosmetic or dermatological preparations comprising N-acetylcysteine ZAMBON S.P.A. (IT) 2012-10-16 US disclosed
CN-101489523-B Cosmetic or dermatological preparations comprising N-acetylcysteine ZAMBON S.P.A. (IT) 2012-02-01 CN disclosed
EP-2046277-B1 COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING N-ACETYLCYSTEINE ZAMBON SPA (IT) 2011-01-19 EP disclosed
US-20100021399-A1 COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING N-ACETYLCYSTEINE ZAMBON S.P.A (IT) 2010-01-28 US disclosed
CN-101489523-A Cosmetic or dermatological preparations comprising n-acetylcysteine ZAMBON SPA (IT) 2009-07-22 CN disclosed
EP-2046277-A1 COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING N-ACETYLCYSTEINE ZAMBON S.p.A. (IT) 2009-04-15 EP disclosed
WO-2008012220-A1 COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING N-ACETYLCYSTEINE ZAMBON S.P.A. (IT) 2008-01-31 WO disclosed