Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10332987 | 0.91 | CCR1 (0.49) | KMT2AMAPTMEN1NPC1PAX8 | |
| SCHEMBL10333242 | 0.89 | MAPT (0.43) | L3MBTL1KMT2AMAPTMEN1NPC1 | |
| Dimethylcarbate SCHEMBL10333388 | 0.83 | CCR1 (0.40) | L3MBTL1KMT2AMAPTMEN1NPC1 | |
| Dimethylcarbate SCHEMBL10333389 | 0.83 | CCR1 (0.40) | L3MBTL1KMT2AMAPTMEN1NPC1 | |
| SCHEMBL10615153 | 0.79 | CCR1 (0.49) | L3MBTL1KMT2AMAPTMEN1NPC1 | |
| SCHEMBL7237609 | 0.78 | CCR1 (0.50) | L3MBTL1KMT2AMAPTMEN1NPC1 | |
| SCHEMBL10333240 | 0.77 | CCR1 (0.40) | L3MBTL1KMT2AMAPTMEN1NPC1 | |
| SCHEMBL2653522 | 0.77 | CCR1 (0.49) | KMT2AMAPTMEN1NPC1CCR1 | |
| SCHEMBL23457094 | 0.72 | TSHR (0.52) | KMT2AMAPTMEN1NPC1PAX8 | |
| SCHEMBL7232304 | 0.71 | CCR1 (0.47) | L3MBTL1KMT2AMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4900751-A | 2-Pyridinyl-phenyl-sulphinyl-and-phenyl-thio-benzimidazoles having antiflammatory or gastic acid secretion inhibition activity | FISONS PLC (GB) | 1990-02-13 | — | — | US | disclosed |