Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylcarbate SCHEMBL10333389 | 1.00 | CCR1 (0.40) | CCR1CCR5CCR8GAAMAPK1 | |
| SCHEMBL10615153 | 0.91 | CCR1 (0.49) | CCR1CCR5CCR8MAPK1HTT | |
| SCHEMBL10333239 | 0.83 | L3MBTL1 (0.46) | CCR1CCR5CCR8GAANPSR1 | |
| SCHEMBL10333242 | 0.80 | MAPT (0.43) | CCR1CCR5CCR8GAANPSR1 | |
| SCHEMBL10332987 | 0.79 | CCR1 (0.49) | CCR1CCR5CCR8GAAMAPK1 | |
| SCHEMBL7237609 | 0.78 | CCR1 (0.50) | CCR1CCR5CCR8HTTNPSR1 | |
| SCHEMBL10333240 | 0.77 | CCR1 (0.40) | CCR1CCR5CCR8GAAHTT | |
| SCHEMBL2653522 | 0.77 | CCR1 (0.49) | CCR1CCR5CCR8HTTCTSV | |
| SCHEMBL7232304 | 0.71 | CCR1 (0.47) | CCR1CCR5CCR8GAAMAPK1 | |
| SCHEMBL7230510 | 0.69 | NFE2L2 (0.58) | CCR1CCR5CCR8KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4900751-A | 2-Pyridinyl-phenyl-sulphinyl-and-phenyl-thio-benzimidazoles having antiflammatory or gastic acid secretion inhibition activity | FISONS PLC (GB) | 1990-02-13 | — | — | US | disclosed |
| EP-0262845-A1 | Heterocyclic substituted azole derivatives | FISONS plc (GB) | 1988-04-06 | — | — | EP | disclosed |