SCHEMBL10333311

SCHEMBL10333311

CCCCCCCCOc1ccc(-c2ccc([C@@H](C)O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.59
NR5A1 Q13285 1/20 0.57
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
TP53 P04637 1/20 0.51
TSHR P16473 1/20 0.51
SLC2A1 P11166 1/20 0.51
LMNA P02545 1/20 0.51
MMP9 P14780 1/20 0.51
MMP8 P22894 1/20 0.51
MMP13 P45452 1/20 0.51
PLA2G4B P0C869 2/20 0.50
LTA4H P09960 1/20 0.50
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9127799 1.00 RARB (0.59) RARBNR5A1CYP3A4CYP2D6TP53
SCHEMBL10333045 0.95 NR5A1 (0.62) RARBNR5A1TP53TSHRSLC2A1
SCHEMBL9808863 0.95 NR5A1 (0.62) RARBNR5A1TP53TSHRSLC2A1
SCHEMBL9478810 0.95 NR5A1 (0.62) RARBNR5A1TP53TSHRSLC2A1
SCHEMBL9126010 0.92 NR5A1 (0.53) RARBNR5A1CYP3A4CYP2D6TP53
SCHEMBL677559 0.87 RARB (0.58) RARBNR5A1CYP3A4CYP2D6TP53
SCHEMBL12537108 0.87 RARB (0.58) RARBNR5A1CYP3A4CYP2D6TP53
SCHEMBL18314262 0.87 RARB (0.58) RARBNR5A1CYP3A4CYP2D6TP53
SCHEMBL17946790 0.87 RARB (0.58) RARBNR5A1CYP3A4CYP2D6TP53
SCHEMBL18868408 0.86 L3MBTL1 (0.49) NR5A1LTA4HPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4916074-A ENZYMATIC TRANS ESTERIFICATION OF ALCOHOL WITH TRIGLYCERIDES; PSEUDOMONAS-DERIVED ENZYME CHISSO CORPORATION (JP) 1990-04-10 US disclosed