SCHEMBL10334261

SCHEMBL10334261

Cc1c(S(=O)(=O)c2ccc(C(=O)O)c(C(=O)O)c2C)ccc(C(=O)O)c1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.38
ALOX15 P16050 2/20 0.38
HAAO P46952 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
GABRA4 P48169 1/20 0.35
GABRE P78334 1/20 0.35
GABRA6 Q16445 1/20 0.35
GABRG1 Q8N1C3 1/20 0.35
GABRG3 Q99928 1/20 0.35
GABRQ Q9UN88 1/20 0.35
ALDH1A1 P00352 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10333650 0.85 POLB (0.47) ALDH1A1HSD17B10HPGDCA2CDC25B
SCHEMBL6334298 0.79 CYP1A2 (0.48) CYP1A2ALOX15HAAOGABRPGABRD
SCHEMBL10333885 0.77 TSHR (0.38) CYP1A2ALOX15ALDH1A1HPGDCA1
SCHEMBL27316603 0.76 ALDH1A1 (0.40) CYP1A2ALOX15HAAOGABRPGABRD
SCHEMBL139141 0.75 CYP1A2 (0.44) CYP1A2ALOX15HAAOGABRPGABRD
SCHEMBL1501399 0.75 CYP1A2 (0.44) CYP1A2ALOX15HAAOGABRPGABRD
SCHEMBL29400914 0.75 CYP1A2 (0.44) CYP1A2ALOX15HAAOGABRPGABRD
SCHEMBL27412126 0.74 NPSR1 (0.44) ALDH1A1HPGDMMP1MMP2MMP9
Benzene SCHEMBL28845411 0.74 ALDH1A1 (0.46) CYP1A2ALOX15HAAOALDH1A1HSD17B10
SCHEMBL4123194 0.74 SELL (0.50) CYP1A2ALOX15ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4914231-A RECRYSTALLIZING FROM WATER-ACETIC ACID MIXTURE NEW JAPAN CHEMICAL CO., LTD. (JP) 1990-04-03 US disclosed