Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035679 | 0.81 | CCR2 (0.44) | CCR2CYP2C9KCNH2 | |
| SCHEMBL18714270 | 0.75 | CCR2 (0.63) | CCR2CYP2C9 | |
| SCHEMBL1038174 | 0.73 | CYP2C9 (0.46) | CCR2CYP2C9KCNH2 | |
| SCHEMBL1037006 | 0.73 | CCR2 (0.44) | CCR2CYP2C9KCNH2 | |
| SCHEMBL14305545 | 0.72 | CYP2C9 (0.43) | CCR2CYP2C9KCNH2 | |
| SCHEMBL3533098 | 0.71 | CYP2C9 (0.47) | CCR2CYP2C9 | |
| SCHEMBL1037160 | 0.71 | CYP2C9 (0.43) | CCR2CYP2C9KCNH2 | |
| SCHEMBL1033968 | 0.71 | CCR2 (0.51) | CCR2CYP2C9 | |
| SCHEMBL1957811 | 0.70 | CCR2 (0.60) | CCR2CYP2C9KCNH2 | |
| SCHEMBL1033635 | 0.70 | CCR2 (0.52) | CCR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049515-B1 | TRIAZOLYL PYRIDYL BENZENESULFONAMIDES AS CCR2 OR CCR9 MODULATORS FOR THE TREATMENT OF ATHEROSCLEROSIS | CHEMOCENTRYX INC (US) | 2011-01-26 | — | — | EP | claimed |