Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | TFPI | P10646 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.43 |
| ▸ | PTH1R | Q03431 | 3/20 | 0.43 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 2/20 | 0.42 |
| ▸ | NPY2R | P49146 | 2/20 | 0.42 |
| ▸ | NPY4R | P50391 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10336101 | 1.00 | RXFP1 (0.52) | RXFP1KEAP1TFPIGRIN2DGRIN3B | |
| SCHEMBL9346849 | 0.94 | RXFP1 (0.52) | RXFP1KEAP1TFPIGRIN2DGRIN3B | |
| SCHEMBL9346837 | 0.94 | RXFP1 (0.52) | RXFP1KEAP1TFPIGRIN2DGRIN3B | |
| SCHEMBL29860422 | 0.92 | RXFP1 (0.49) | RXFP1TFPIECE1GLP1RMUS81 | |
| SCHEMBL29601319 | 0.90 | RXFP1 (0.50) | RXFP1KEAP1TFPIECE1GLP1R | |
| SCHEMBL29601022 | 0.90 | RXFP1 (0.50) | RXFP1KEAP1TFPIECE1GLP1R | |
| SCHEMBL607984 | 0.89 | NOD1 (0.40) | RXFP1GLP1RNPY1RNPY2RNPY4R | |
| SCHEMBL30563214 | 0.89 | NOD1 (0.40) | RXFP1TFPINPY1RNPY2RNPY4R | |
| SCHEMBL607985 | 0.89 | NOD1 (0.40) | RXFP1GLP1RNPY1RNPY2RNPY4R | |
| SCHEMBL30389981 | 0.89 | RXFP1 (0.55) | RXFP1KEAP1TFPIGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245362-A4 | SYNTHETIC PEPTIDES AND USE FOR DIAGNOSIS AND VACCINATION FOR AIDS AND ARC. | SOUTHWEST FOUND BIOMED RES (US) | 1990-04-10 | — | — | EP | claimed |
| EP-0245362-A1 | SYNTHETIC PEPTIDES AND USE FOR DIAGNOSIS AND VACCINATION FOR AIDS AND ARC. | SOUTHWEST FOUND BIOMED RES (US) | 1987-11-19 | — | — | EP | claimed |
| WO-1987002775-A1 | SYNTHETIC PEPTIDES AND USE FOR DIAGNOSIS AND VACCINATION FOR AIDS AND ARC | SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH (US) | 1987-05-07 | — | — | WO | claimed |