SCHEMBL1033692

SCHEMBL1033692

CCN(CC)CC[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2471432 0.83 NPSR1 (0.35)
SCHEMBL2439293 0.82 CA12 (0.35)
SCHEMBL2470745 0.81 SIGMAR1 (0.36)
SCHEMBL11622085 0.79 PAOX (0.36)
SCHEMBL7379222 0.79 PAOX (0.36)
SCHEMBL7673852 0.76 CA12 (0.38)
SCHEMBL2385651 0.74
SCHEMBL10769544 0.74 KDM4E (0.34)
SCHEMBL10350737 0.71
SCHEMBL10615158 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140309192-A1 MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC, 2014-10-16 US claimed
EP-2776407-A1 MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO Arena Pharmaceuticals, Inc. (US) 2014-09-17 EP claimed
EP-2054411-B1 NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AMOREPACIFIC CORP (KR) 2014-08-20 EP claimed
WO-2013070657-A1 MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2013-05-16 WO claimed
US-6380197-B1 FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES AVENTIS PHARMA S. A. (FR) 2002-04-30 US claimed
EP-1001943-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2000-05-24 EP claimed
WO-1999003843-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1999-01-28 WO claimed
US-5760011-A USEFUL AGAINST BACTERIAL AND MYCOPLASMIC PATHOGENS PFIZER INC. (US) 1998-06-02 US claimed
EP-0649430-B1 DERIVATIVES OF 16-MEMBERED RING ANTIBIOTIC MACROLIDES PFIZER (US) 1997-12-17 EP claimed
US-5677287-A TREATS MYCOPLASMIC INFECTIONS PFIZER INC. (US) 1997-10-14 US claimed
EP-0333174-B1 Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO (JP) 1996-05-08 EP claimed
EP-0708770-A1 AMIDE DERIVATIVES OF 16-MEMBERED RING ANTIBIOTIC MACROLIDES PFIZER (US) 1996-05-01 EP claimed
WO-1996009312-A1 ANTIBIOTIC MACROLIDES PFIZER INC. (US) 1996-03-28 WO claimed
EP-0649430-A1 DERIVATIVES OF 16-MEMBERED RING ANTIBIOTIC MACROLIDES PFIZER INC. (US) 1995-04-26 EP claimed
WO-1995002594-A1 AMIDE DERIVATIVES OF 16-MEMBERED RING ANTIBIOTIC MACROLIDES PFIZER INC. (US) 1995-01-26 WO claimed
WO-1994021657-A1 ANTIBACTERIAL 16-MEMBERED RING MACROLIDES CONTAINING OLEFINS AT C-20 PFIZER INC. (US) 1994-09-29 WO claimed
CN-1083068-A The derivative of the macrolide of 16 membered ring antibiotics PFIZER (US) 1994-03-02 CN claimed
WO-1994002496-A1 DERIVATIVES OF 16-MEMBERED RING ANTIBIOTIC MACROLIDES PFIZER INC. (US) 1994-02-03 WO claimed
US-5187156-A D-Tryptophan- and Phenylalanine-containing tripeptides as tachykinin antagonists; asthma FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-02-16 US claimed
EP-0333174-A2 Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-09-20 EP claimed