Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.50 |
| ▸ | NPY1R | P25929 | 9/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.50 |
| ▸ | NPY2R | P49146 | 5/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.43 |
| ▸ | CALCR | P30988 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337129 | 1.00 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2RNOD1 | |
| SCHEMBL30997457 | 0.89 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RRAMP3 | |
| SCHEMBL31000055 | 0.89 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2RNOD1 | |
| SCHEMBL30596211 | 0.89 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL31721011 | 0.88 | NPY4R (0.53) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31319515 | 0.87 | RAMP3 (0.48) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL30903466 | 0.87 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31752429 | 0.87 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31567752 | 0.87 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29815714 | 0.87 | TFPI (0.47) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0380546-A1 | POLYPEPTIDES WITH TYPE IV COLLAGEN ACTIVITY. | UNIV MINNESOTA (US) | 1990-08-08 | — | — | EP | claimed |
| WO-1989003392-A1 | POLYPEPTIDES WITH TYPE IV COLLAGEN ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-04-20 | — | — | WO | claimed |