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SCHEMBL10337129

SCHEMBL10337129

CC(C)C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](C)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 14/20 0.50
▸ NPY1R P25929 9/20 0.50
▸ NPY5R Q15761 8/20 0.50
▸ NPY2R P49146 5/20 0.50
▸ NOD1 Q9Y239 1/20 0.44
▸ KEAP1 Q14145 1/20 0.43
▸ RAMP3 O60896 3/20 0.43
▸ CALCR P30988 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10337128 1.00 NPY4R (0.50) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL30997457 0.89 NPY4R (0.47) NPY4RNPY1RNPY5RNPY2RRAMP3
SCHEMBL31000055 0.89 NPY4R (0.49) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL30596211 0.89 NPY4R (0.46) NPY4RNPY1RNPY5RNPY2RKEAP1
SCHEMBL31721011 0.88 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31319515 0.87 RAMP3 (0.48) NPY4RNPY1RNPY5RNPY2RKEAP1
SCHEMBL30903466 0.87 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31752429 0.87 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31567752 0.87 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29815714 0.87 TFPI (0.47) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0380546-A1 POLYPEPTIDES WITH TYPE IV COLLAGEN ACTIVITY. UNIV MINNESOTA (US) 1990-08-08 — — EP claimed
WO-1989003392-A1 POLYPEPTIDES WITH TYPE IV COLLAGEN ACTIVITY REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1989-04-20 — — WO claimed
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