Methane

Methane

SCHEMBL10337285

C.C.C.C.C.C.N=C=O.N=C=O.NC(=O)NC(N)=O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.43
TSHR P16473 2/20 0.37
NFKB1 P19838 2/20 0.37
LMNA P02545 2/20 0.37
CYP1A2 P05177 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
THPO P40225 1/20 0.37
CA2 P00918 1/20 0.37
CYP3A4 P08684 1/20 0.37
CA5A P35218 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491201 0.97 CRBN (0.45) CRBNTSHRNFKB1LMNACYP1A2
SCHEMBL5474405 0.97 CRBN (0.45) CRBNTSHRNFKB1LMNACYP1A2
SCHEMBL476197 0.97 CRBN (0.45) CRBNTSHRNFKB1LMNACYP1A2
SCHEMBL30549399 0.97 CRBN (0.45) CRBNTSHRNFKB1LMNACYP1A2
Urea SCHEMBL27737691 0.94 CRBN (0.43) CRBNTSHRNFKB1LMNACYP1A2
SCHEMBL28324604 0.88 TSHR (0.40) CRBNTSHRNFKB1LMNACYP1A2
Cyclohexane SCHEMBL28164824 0.88 CRBN (0.39) CRBNTSHRNFKB1LMNACYP1A2
Carbimide SCHEMBL10692895 0.87 CRBN (0.47) CRBNTSHRNFKB1LMNACYP1A2
Methane SCHEMBL676366 0.86 CRBN (0.38) CRBNTSHRNFKB1LMNACYP1A2
Methane SCHEMBL8333924 0.86 CRBN (0.38) CRBNTSHRNFKB1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106947372-A The application composition of NH functional prepolymers comprising polyisocyanates chain extension 涂层国外知识产权有限公司 2017-07-14 CN claimed
US-4977028-A Laminated transparent polarizing glasses and method of making CORNING INCORPORATED (US) 1990-12-11 US claimed
US-4865668-A Laminated transparent polarizing glasses and method of making CORNING INCORPORATED (US) 1989-09-12 US claimed
EP-0077168-B1 METHOD FOR MAKING LAMINATED OPHTHALMIC LENSES Corning Glass Works (US) 1986-03-26 EP disclosed
EP-0077168-A1 Method for making laminated ophthalmic lenses Corning Glass Works (US) 1983-04-20 EP disclosed