Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5474405 | 0.90 | CRBN (0.45) | CRBNLMNATSHRNFKB1CYP1A2 | |
| SCHEMBL476197 | 0.90 | CRBN (0.45) | CRBNLMNATSHRNFKB1CYP1A2 | |
| SCHEMBL491201 | 0.90 | CRBN (0.45) | CRBNLMNATSHRNFKB1CYP1A2 | |
| SCHEMBL30549399 | 0.90 | CRBN (0.45) | CRBNLMNATSHRNFKB1CYP1A2 | |
| Carbimide SCHEMBL11668505 | 0.88 | CRBN (0.39) | CRBNLMNATSHRNFKB1CYP1A2 | |
| Urea SCHEMBL27737691 | 0.87 | CRBN (0.43) | CRBNLMNATSHRNFKB1CYP1A2 | |
| Methane SCHEMBL10337285 | 0.87 | CRBN (0.43) | CRBNLMNATSHRNFKB1CYP1A2 | |
| SCHEMBL27939070 | 0.84 | CRBN (0.60) | CRBNLMNATSHRNFKB1CYP1A2 | |
| SCHEMBL27524722 | 0.84 | CRBN (0.60) | CRBNLMNATSHRNFKB1CYP1A2 | |
| SCHEMBL15045 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101616698-A | Treated ECM material with enhanced compositional properties | COOK BIOTECH INC | 2009-12-30 | — | — | CN | disclosed |
| CN-1295602-A | Coloured polyurethanes | AVECIA LTD (GB) | 2001-05-16 | — | — | CN | disclosed |
| EP-0257441-A2 | Flexible polyurethane foams based on difunctional polyols and MDI and method for preparing the same | THE DOW CHEMICAL COMPANY (US) | 1988-03-02 | — | — | EP | disclosed |