Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.61 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.61 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine Methyl Ester SCHEMBL28872878 | 1.00 | ESR1 (0.61) | ESR1ESR2SLC7A5MIFTAAR1 | |
| Tyrosine Methyl Ester SCHEMBL9818526 | 0.98 | ESR1 (0.59) | ESR1ESR2SLC7A5MIFTAAR1 | |
| Tyrosine Methyl Ester SCHEMBL313051 | 0.98 | ESR1 (0.63) | ESR1ESR2SLC7A5MIFTAAR1 | |
| Tyrosine Methyl Ester SCHEMBL1255129 | 0.98 | ESR1 (0.63) | ESR1ESR2SLC7A5MIFTAAR1 | |
| Tyrosine Methyl Ester SCHEMBL314923 | 0.98 | ESR1 (0.63) | ESR1ESR2SLC7A5MIFTAAR1 | |
| Tyrosine Methyl Ester SCHEMBL1255128 | 0.97 | ESR1 (0.61) | ESR1ESR2SLC7A5MIFTAAR1 | |
| Tyrosine Methyl Ester SCHEMBL919401 | 0.97 | ESR1 (0.61) | ESR1ESR2SLC7A5MIFTAAR1 | |
| Tyrosine Methyl Ester SCHEMBL945724 | 0.97 | ESR1 (0.61) | ESR1ESR2SLC7A5MIFTAAR1 | |
| Tyrosine Methyl Ester SCHEMBL7389911 | 0.95 | ESR1 (0.59) | ESR1ESR2SLC7A5MIFTAAR1 | |
| Tyrosine Methyl Ester SCHEMBL22390809 | 0.93 | ESR1 (0.58) | ESR1ESR2SLC7A5MIFTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295294-A4 | PEPTIDYLAMINODIOLS. | ABBOTT LAB (US) | 1990-04-10 | — | — | EP | disclosed |
| EP-0295294-A1 | PEPTIDYLAMINODIOLS | ABBOTT LABORATORIES (US) | 1988-12-21 | — | — | EP | disclosed |
| WO-1988005050-A1 | PEPTIDYLAMINODIOLS | ABBOTT LABORATORIES (US) | 1988-07-14 | — | — | WO | disclosed |