Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3312647 | 0.82 | ALDH1A1 (0.57) | ALDH1A1TDP1SMN1; SMN2TSHREPHX1 | |
| SCHEMBL10482100 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHREPHX1 | |
| SCHEMBL9501546 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHREPHX1 | |
| SCHEMBL16177 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHREPHX1 | |
| SCHEMBL6376906 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHREPHX1 | |
| SCHEMBL262010 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHREPHX1 | |
| SCHEMBL6377533 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHREPHX1 | |
| SCHEMBL12977796 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHREPHX1 | |
| SCHEMBL260571 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHREPHX1 | |
| SCHEMBL8901543 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378657-A1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS. | RAJADHYAKSHA VITHAL J | 1990-07-25 | — | — | EP | disclosed |
| WO-1990000407-A1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS | RAJADHYAKSHA VITHAL J (US) | 1990-01-25 | — | — | WO | disclosed |