Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 18/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 17/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.64 |
| ▸ | HTR3A | P46098 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15568527 | 0.87 | HRH1 (0.66) | HRH1CYP2D6CHRM1KCNH2HTR3A | |
| SCHEMBL27317913 | 0.85 | HRH1 (0.69) | HRH1CYP2D6CHRM1KCNH2HTR3A | |
| SCHEMBL5226378 | 0.85 | HRH1 (1.00) | HRH1CYP2D6CHRM1KCNH2HTR3A | |
| SCHEMBL31553435 | 0.85 | HRH1 (1.00) | HRH1CYP2D6CHRM1KCNH2HTR3A | |
| Water SCHEMBL10337970 | 0.84 | HRH1 (0.98) | HRH1CYP2D6CHRM1KCNH2HTR3A | |
| SCHEMBL5229655 | 0.83 | HRH1 (0.73) | HRH1CYP2D6CHRM1KCNH2HTR3A | |
| SCHEMBL11479448 | 0.83 | SSTR5 (0.81) | HRH1CYP2D6CHRM1KCNH2HTR3A | |
| Trifluoroacetic Acid SCHEMBL15567418 | 0.83 | HRH1 (0.59) | HRH1CYP2D6CHRM1KCNH2HTR3A | |
| SCHEMBL15568620 | 0.82 | HRH1 (0.63) | HRH1CYP2D6CHRM1KCNH2HTR3A | |
| SCHEMBL10483537 | 0.82 | HRH1 (0.80) | HRH1CYP2D6CHRM1KCNH2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912219-A | 2-[4-pyrimidin-2-yl amino)piperidin-1-yl]benzimidazole compound | SYNTHELABO (FR) | 1990-03-27 | — | — | US | disclosed |
| US-4820710-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIINFLAMMATORY AGENTS | SYNTHELABO (FR) | 1989-04-11 | — | — | US | disclosed |