Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 19/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 18/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.69 |
| ▸ | HTR3A | P46098 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18292404 | 0.88 | HRH1 (0.65) | HRH1CYP2D6KCNH2CHRM1HTR3A | |
| SCHEMBL5229655 | 0.87 | HRH1 (0.73) | HRH1CYP2D6KCNH2CHRM1HTR3A | |
| SCHEMBL10337607 | 0.85 | HRH1 (0.74) | HRH1CYP2D6KCNH2CHRM1HTR3A | |
| SCHEMBL10337972 | 0.85 | HRH1 (0.73) | HRH1CYP2D6KCNH2CHRM1HTR3A | |
| SCHEMBL15568131 | 0.84 | HRH1 (0.61) | HRH1CYP2D6KCNH2CHRM1HTR3A | |
| SCHEMBL10464589 | 0.84 | HRH1 (0.69) | HRH1CYP2D6KCNH2CHRM1HTR3A | |
| SCHEMBL15568527 | 0.84 | HRH1 (0.66) | HRH1CYP2D6KCNH2CHRM1HTR3A | |
| SCHEMBL15474498 | 0.83 | PDE6D (0.66) | HRH1CYP2D6KCNH2CHRM1HTR3A | |
| SCHEMBL15452490 | 0.83 | HRH1 (0.65) | HRH1CYP2D6KCNH2CHRM1HTR3A | |
| SCHEMBL10483537 | 0.83 | HRH1 (0.80) | HRH1CYP2D6KCNH2CHRM1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1028103-C | Preparation method of piperidyl benzimidazole compound | MERRELL DOW PHARMA (US) | 1995-04-05 | — | — | CN | disclosed |
| CN-1041940-A | PIPERIDINYL BENZIMIDAZOLES | MERRELL DOW PHARMA (US) | 1990-05-09 | — | — | CN | disclosed |