Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.38 |
| ▸ | F3 | P13726 | 2/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350607 | 0.98 | TSHR (0.64) | TSHRFAAHTRPV1ALDH1A1EPHX1 | |
| SCHEMBL8629602 | 0.98 | TSHR (0.64) | TSHRFAAHTRPV1ALDH1A1EPHX1 | |
| SCHEMBL27746883 | 0.98 | TSHR (0.64) | TSHRFAAHTRPV1ALDH1A1EPHX1 | |
| SCHEMBL4214619 | 0.98 | TSHR (0.64) | TSHRFAAHTRPV1ALDH1A1EPHX1 | |
| SCHEMBL28773679 | 0.98 | TSHR (0.64) | TSHRFAAHTRPV1ALDH1A1EPHX1 | |
| SCHEMBL10337470 | 0.95 | — | — | |
| SCHEMBL27519552 | 0.93 | — | — | |
| SCHEMBL10579601 | 0.82 | TSHR (0.52) | TSHRFAAHTRPV1ALDH1A1EP300 | |
| SCHEMBL10579490 | 0.82 | TSHR (0.52) | TSHRFAAHTRPV1ALDH1A1EP300 | |
| SCHEMBL11852314 | 0.82 | TSHR (0.46) | TSHRFAAHTRPV1ALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960771-A | TRANSDERMAL DELIVERY OF THERAPEUTIC AGENTS; DRUGS, SUNSCREENS, INSECT REPELLENTS, COSMETICS | LVMH MOET HENNESSY LOUIS VUITTON, INC. | 1990-10-02 | — | — | US | disclosed |
| EP-0378657-A1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS. | RAJADHYAKSHA VITHAL J | 1990-07-25 | — | — | EP | disclosed |
| WO-1990000407-A1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS | RAJADHYAKSHA VITHAL J (US) | 1990-01-25 | — | — | WO | disclosed |