SCHEMBL8629602

SCHEMBL8629602

CCCCCCCCCCCCCC[CH]CC=O

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.64
FAAH O00519 2/20 0.56
TRPV1 Q8NER1 2/20 0.56
ALDH1A1 P00352 2/20 0.41
EPHX1 P07099 1/20 0.41
ADH1B P00325 1/20 0.41
ADH1C P00326 1/20 0.41
ADH1A P07327 1/20 0.41
ADH4 P08319 1/20 0.41
ADH7 P40394 1/20 0.41
THRB P10828 1/20 0.40
EP300 Q09472 1/20 0.40
DUSP3 P51452 1/20 0.39
PTPN7 P35236 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4214619 1.00 TSHR (0.64) TSHRFAAHTRPV1ALDH1A1EPHX1
SCHEMBL27746883 1.00 TSHR (0.64) TSHRFAAHTRPV1ALDH1A1EPHX1
SCHEMBL350607 1.00 TSHR (0.64) TSHRFAAHTRPV1ALDH1A1EPHX1
SCHEMBL28773679 1.00 TSHR (0.64) TSHRFAAHTRPV1ALDH1A1EPHX1
SCHEMBL10337668 0.98 TSHR (0.61) TSHRFAAHTRPV1ALDH1A1EPHX1
SCHEMBL10337470 0.97
SCHEMBL27519552 0.90
SCHEMBL10579601 0.84 TSHR (0.52) TSHRFAAHTRPV1ALDH1A1THRB
SCHEMBL10579490 0.84 TSHR (0.52) TSHRFAAHTRPV1ALDH1A1THRB
SCHEMBL10448536 0.82 TSHR (0.84) TSHRFAAHTRPV1ALDH1A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103524559-B Ester derivant of polysubstituted 4-methylamino benzenecarboximidamide and its production and use 西藏海思科药业集团股份有限公司 2016-09-28 CN disclosed
EP-0847437-A1 ALKYL ETHER AMINE CONVEYOR LUBRICANT ECOLAB INC. (US) 1998-06-17 EP disclosed
WO-1997045508-A1 ALKYL ETHER AMINE CONVEYOR LUBRICANT ECOLAB INC. (US) 1997-12-04 WO disclosed
US-5310542-A Aldobioamides LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1994-05-10 US disclosed
EP-0551675-A1 Oral hygiene compositions containing antiplaque agents UNILEVER N.V. (NL) 1993-07-21 EP disclosed