Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744365 | 0.81 | TP53 (0.45) | TP53TSHRCA1CA2GAA | |
| SCHEMBL16173839 | 0.80 | TSHR (0.48) | TP53TSHRCA1CA2GAA | |
| SCHEMBL5819260 | 0.80 | CA1 (0.52) | TP53TSHRCA1CA2LMNA | |
| SCHEMBL2917048 | 0.80 | TSHR (0.48) | TP53TSHRCA1CA2GAA | |
| SCHEMBL21403433 | 0.76 | PPARD (0.40) | MAPTL3MBTL1 | |
| SCHEMBL148644 | 0.75 | CNR1 (0.45) | TP53TSHRCA1CA2GAA | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL28519 | 0.74 | GAA (0.64) | TP53TSHRCA1CA2GAA | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL28239475 | 0.74 | GAA (0.64) | TP53TSHRCA1CA2GAA | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL29579232 | 0.74 | GAA (0.64) | TP53TSHRCA1CA2GAA | |
| SCHEMBL1805490 | 0.74 | CA2 (0.56) | TP53TSHRCA1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001420-A | — | — | None | — | — | JP | disclosed |
| JP-H021420-A | ALKYL OR BENZYL PHENOL ETHER, ITS PREPARATION AND ITS THERAPEUTIC USE | DELALANDE SA | 1990-01-05 | — | — | JP | disclosed |