Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.48 |
| ▸ | CALML3 | P27482 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SDHA | P31040 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1033802 | 1.00 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL1033523 | 0.99 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL1033525 | 0.99 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL3090485 | 0.89 | CALML3 (0.43) | MAOACALML3MAOBCYP3A4CYP2C19 | |
| SCHEMBL17749421 | 0.88 | MAOA (0.49) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1037132 | 0.87 | MAOA (0.54) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL10197587 | 0.87 | MAOA (0.54) | MAOACALML3MAOBLMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL1034925 | 0.87 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL1034922 | 0.87 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL17749416 | 0.87 | MAOA (0.47) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904489-B1 | PROCESS FOR THE SYNTHESIS OF TRIAZOLES | RIB X PHARMACEUTICALS INC (US) | 2011-01-26 | — | — | EP | disclosed |