Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.66 |
| ▸ | APEX1 | P27695 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | ESR1 | P03372 | 2/20 | 0.66 |
| ▸ | PGR | P06401 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | PPARG | P37231 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693180 | 0.92 | TDP1 (0.68) | TDP1MAPTHSD17B10NR1I2APEX1 | |
| SCHEMBL10693043 | 0.91 | TDP1 (0.68) | TDP1MAPTHSD17B10NR1I2APEX1 | |
| SCHEMBL10693678 | 0.90 | TDP1 (0.71) | TDP1MAPTHSD17B10NR1I2APEX1 | |
| SCHEMBL8988471 | 0.90 | TDP1 (0.71) | TDP1MAPTHSD17B10NR1I2APEX1 | |
| SCHEMBL9845579 | 0.90 | TDP1 (0.71) | TDP1MAPTHSD17B10NR1I2APEX1 | |
| SCHEMBL10695061 | 0.89 | TDP1 (0.66) | TDP1MAPTHSD17B10NR1I2APEX1 | |
| SCHEMBL8177096 | 0.89 | TDP1 (0.69) | TDP1MAPTHSD17B10NR1I2APEX1 | |
| SCHEMBL9813320 | 0.89 | TDP1 (0.69) | TDP1MAPTHSD17B10NR1I2APEX1 | |
| SCHEMBL9845771 | 0.89 | TDP1 (0.69) | TDP1MAPTHSD17B10NR1I2APEX1 | |
| SCHEMBL9762908 | 0.89 | TDP1 (0.69) | TDP1MAPTHSD17B10NR1I2APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2049791-A | — | — | None | — | — | JP | disclosed |
| JP-H0249791-A | 3-(1-BENZYLPYRIDINIUM)THIOMETHYLCEPHALOSPORIN DERIVATIVE | BANYU PHARMACEUT CO LTD | 1990-02-20 | — | — | JP | disclosed |