SCHEMBL10338149

SCHEMBL10338149

C=CCOC(=S)CC(C)C

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.31
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29655291 0.77 ALDH1A1 (0.32) TDP1
SCHEMBL10081183 0.76 TDP1 (0.42) TDP1TSHRCYP3A4
SCHEMBL10595844 0.75
SCHEMBL873242 0.74 TDP1 (0.58) TDP1TSHRCYP3A4
SCHEMBL10598508 0.73
SCHEMBL28366697 0.72 TDP1 (0.36) TDP1TSHR
Ethane SCHEMBL17791907 0.72 TDP1 (0.61) TDP1TSHRCYP3A4
SCHEMBL10338117 0.72 ALDH1A1 (0.38) TDP1TSHR
SCHEMBL1537282 0.70 CYP3A4 (0.43) TSHRCYP3A4APP
SCHEMBL27955078 0.69 TDP1 (0.38) TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2003673-A None JP disclosed
JP-2003673-A None JP disclosed
JP-H023673-A ALKYL 3-METHYLTHIO-BTYRATE, FLAVOR COMPOSITION CONTAINING AT LEAST ONE SUCH COMPOUND AS FLAVOR COMPONENT, AND FOOD AND EXCITATORY FOOD AND DRINK FLAVORED WITH THE SAME NAARDEN INTERNATL NV 1990-01-09 JP disclosed
JP-H023673-A ALKYL 3-METHYLTHIO-BTYRATE, FLAVOR COMPOSITION CONTAINING AT LEAST ONE SUCH COMPOUND AS FLAVOR COMPONENT, AND FOOD AND EXCITATORY FOOD AND DRINK FLAVORED WITH THE SAME NAARDEN INTERNATL NV 1990-01-09 JP disclosed