SCHEMBL10338153

SCHEMBL10338153

O=C(O)c1c(O)ccoc1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.52
MAPK1 P28482 1/20 0.52
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
DPP4 P27487 1/20 0.34
LMNA P02545 1/20 0.33
MAOA P21397 1/20 0.33
CYP3A4 P08684 3/20 0.32
ALDH1A1 P00352 3/20 0.32
MAPT P10636 2/20 0.32
THRB P10828 2/20 0.32
HPGD P15428 2/20 0.32
DAO P14920 1/20 0.32
MEN1 O00255 1/20 0.32
TNF P01375 1/20 0.32
HSPD1 P10809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24376271 0.81 KDM4E (0.55) KDM4EMAPK1CA12CA9LMNA
SCHEMBL6659676 0.79 KDM4E (0.48) KDM4EMAPK1CA12CA1CA2
SCHEMBL6668225 0.78 KMT2A (0.40) KDM4EMAPK1CA12CA1CA2
SCHEMBL8079135 0.77 KDM4E (0.45) KDM4EMAPK1LMNACYP3A4ALDH1A1
SCHEMBL7933328 0.76 KDM4E (0.50) KDM4EMAPK1CA12CA1CA2
SCHEMBL6660100 0.72
SCHEMBL17219697 0.71 CA12 (0.39) KDM4EMAPK1CA12CA1CA2
SCHEMBL2971000 0.70 CA1 (0.68) KDM4ECA12CA1CA2CA7
SCHEMBL29419955 0.70 CA1 (0.68) KDM4ECA12CA1CA2CA7
SCHEMBL1781537 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2101071-A None JP disclosed
JP-2059566-A None JP disclosed
US-20240099955-A1 SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF HTL BIOTECHNOLOGY INNOVATION INC. 2024-03-28 US disclosed
EP-4288084-A1 SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF Modern Meadow, Inc. (US) 2023-12-13 EP disclosed
CN-110028470-B Process method for producing dehydroacetic acid, patchoulenone and analogues thereof by using carbon dioxide 南开大学 2021-11-19 CN disclosed
EP-3398585-B1 EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME HAYASHIBARA CO (JP) 2020-02-26 EP disclosed
CN-110028470-A A kind of process using carbon dioxide production dehydroactic acid and Pogostone and the like 南开大学 2019-07-19 CN disclosed
US-20190008747-A1 EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME Hayashibara Co., Ltd. (JP) 2019-01-10 US disclosed
EP-3398585-A1 EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME Hayashibara Co., Ltd. (JP) 2018-11-07 EP disclosed
US-10111822-B2 External dermal composition for anti-ageing and method for producing the same Hayashibara Co., Ltd. (JP) 2018-10-30 US disclosed
EP-2939657-B1 SKIN-EXTERIOR ANTI-AGEING COMPOSITION AND PRODUCTION METHOD THEREFOR HAYASHIBARA CO (JP) 2018-08-08 EP disclosed
US-20150342854-A1 EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME Hayashibara Co., Ltd. (JP) 2015-12-03 US disclosed
EP-2939657-A1 SKIN-EXTERIOR ANTI-AGEING COMPOSITION AND PRODUCTION METHOD THEREFOR Hayashibara Co., Ltd. (JP) 2015-11-04 EP disclosed
JP-H02101071-A PRODUCTION OF DIHYDRO-2H-PYRAN-2,4(3H)-DIONE NIPPON SODA CO LTD 1990-04-12 JP disclosed
JP-H0259566-A PRODUCTION OF 4-HYDROXY-2H-PYRAN-2-ONE NIPPON SODA CO LTD 1990-02-28 JP disclosed