Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338153 | 0.81 | KDM4E (0.52) | KDM4EMAPK1THRBCA9HPGD | |
| SCHEMBL7933328 | 0.79 | KDM4E (0.50) | KDM4EMAPK1CA9MEN1CYP3A4 | |
| SCHEMBL6659676 | 0.78 | KDM4E (0.48) | KDM4EMAPK1THRBCA9HPGD | |
| SCHEMBL15782818 | 0.76 | CA12 (0.47) | KDM4EMAPK1CA9KCNA3CA12 | |
| SCHEMBL6451162 | 0.71 | THRB (0.70) | MAPK1THRBCA9HPGDMEN1 | |
| SCHEMBL27812 | 0.71 | — | — | |
| SCHEMBL580718 | 0.71 | — | — | |
| SCHEMBL24376272 | 0.71 | MAPK1 (0.42) | KDM4EMAPK1KCNA3HPGDLMNA | |
| SCHEMBL27747720 | 0.71 | PTPN1 (0.49) | KDM4ETHRBCA9KCNA3HPGD | |
| SCHEMBL6660100 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127255-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (GB) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127255-A1 | HERBICIDAL COMPOUNDS | DDT, HDHD5, HPD | KDM4E 1006/4885MAPK1 2796/4885THRB 2520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.