Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.60 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.60 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | TLR2 | O60603 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28258462 | 0.99 | SIRT2 (0.59) | SIRT2SIRT1SIRT3SLC6A5ITGB3 | |
| SCHEMBL28258464 | 0.99 | SIRT2 (0.59) | SIRT2SIRT1SIRT3SLC6A5ITGB3 | |
| SCHEMBL28563745 | 0.94 | SLC6A5 (0.67) | SIRT2SIRT1SIRT3SLC6A5ITGB3 | |
| SCHEMBL28563746 | 0.94 | SLC6A5 (0.67) | SIRT2SIRT1SIRT3SLC6A5ITGB3 | |
| SCHEMBL29879976 | 0.89 | MEN1 (0.53) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8823455 | 0.87 | MEN1 (0.52) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| SCHEMBL9838107 | 0.87 | MEN1 (0.53) | SIRT2SIRT1SIRT3 | |
| SCHEMBL22271575 | 0.87 | MEN1 (0.53) | SIRT2SIRT1SIRT3 | |
| SCHEMBL4065856 | 0.87 | MEN1 (0.53) | SIRT2SIRT1SIRT3 | |
| SCHEMBL5017052 | 0.87 | MEN1 (0.53) | SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2091099-A | — | — | None | — | — | JP | disclosed |
| JP-58172399-A | — | — | None | — | — | JP | disclosed |
| JP-H0291099-A | 1-DEOXYMURAMYLPEPTIDE DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1990-03-30 | — | — | JP | disclosed |
| JP-S58172399-A | MURAMYL TRIPEPTIDE DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1983-10-11 | — | — | JP | disclosed |