Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.55 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.54 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.54 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 1/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339112 | 1.00 | ADORA1 (0.55) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL3351897 | 0.89 | ADORA1 (0.63) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL10606033 | 0.83 | NNMT (0.61) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL10600624 | 0.83 | ADORA1 (0.68) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL4649944 | 0.83 | ADORA1 (0.68) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL3450680 | 0.82 | ADORA1 (0.68) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL2519178 | 0.80 | ADORA1 (0.66) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL10602068 | 0.80 | ADORA1 (0.66) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL10712349 | 0.79 | ADORA1 (0.62) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL7424205 | 0.79 | ADORA2A (0.55) | ADORA1P2RY1ADORA2AADORA2BNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2164897-A | — | — | None | — | — | JP | disclosed |
| JP-H02164897-A | S-DIASTEREOMER OF ADENOSINE DERIVATIVE | G D SEARLE & CO | 1990-06-25 | — | — | JP | disclosed |