SCHEMBL10339396

SCHEMBL10339396

CCCN(CCC)c1ccc(C=O)c(OC)c1

nearest known ligand 0.77

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.77
L3MBTL1 Q9Y468 1/20 0.77
SLC16A3 O15427 4/20 0.51
SLC16A1 P53985 4/20 0.51
KDM4E B2RXH2 3/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MEN1 O00255 2/20 0.42
NPC1 O15118 2/20 0.42
POLB P06746 2/20 0.42
RAB9A P51151 2/20 0.42
KMT2A Q03164 2/20 0.42
GFER P55789 1/20 0.42
MAOB P27338 2/20 0.41
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22636012 0.92 ALDH1A1 (0.66) ALDH1A1L3MBTL1SLC16A3SLC16A1KDM4E
SCHEMBL10009803 0.91 ALDH1A1 (0.73) ALDH1A1L3MBTL1SLC16A3SLC16A1KDM4E
SCHEMBL2950989 0.87 ALDH1A1 (1.00) ALDH1A1L3MBTL1SLC16A3SLC16A1KDM4E
SCHEMBL13236413 0.84 ALDH1A1 (0.55) ALDH1A1L3MBTL1SLC16A3SLC16A1KDM4E
SCHEMBL13182636 0.82 ALDH1A1 (0.78) ALDH1A1L3MBTL1SLC16A3SLC16A1KDM4E
SCHEMBL10010371 0.79 ALDH1A1 (0.56) ALDH1A1L3MBTL1SLC16A3SLC16A1MEN1
SCHEMBL10010368 0.79 ALDH1A1 (0.56) ALDH1A1L3MBTL1SLC16A3SLC16A1MEN1
SCHEMBL3689163 0.79 ALDH1A1 (0.56) ALDH1A1L3MBTL1SLC16A3SLC16A1KDM4E
SCHEMBL11696664 0.79 ALDH1A1 (0.47) ALDH1A1L3MBTL1KDM4ETSHRMEN1
SCHEMBL10010678 0.79 SLC16A3 (0.58) ALDH1A1L3MBTL1SLC16A3SLC16A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2212458-A None JP disclosed
JP-H02212458-A 4-AMINO BENZALDEHYDE DERIVATIVE KOKUSAN KAGAKU KK 1990-08-23 JP disclosed