Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339461 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTHDAC1HDAC3HDAC2 | |
| SCHEMBL11591085 | 0.86 | HDAC1 (0.60) | SMN1; SMN2HDAC1HDAC3HDAC2LMNA | |
| SCHEMBL11591466 | 0.86 | HDAC1 (0.60) | SMN1; SMN2HDAC1HDAC3HDAC2LMNA | |
| SCHEMBL10483511 | 0.80 | HDAC1 (0.53) | SMN1; SMN2HDAC1HDAC3HDAC2LMNA | |
| SCHEMBL11591966 | 0.78 | LMNA (0.69) | SMN1; SMN2HDAC1HDAC3HDAC2LMNA | |
| SCHEMBL8413034 | 0.78 | HDAC1 (0.56) | SMN1; SMN2HDAC1HDAC3HDAC2LMNA | |
| SCHEMBL10483317 | 0.77 | HDAC1 (0.56) | SMN1; SMN2HDAC1HDAC3HDAC2LMNA | |
| SCHEMBL11593266 | 0.77 | HDAC1 (0.50) | SMN1; SMN2MAPTHDAC1HDAC3HDAC2 | |
| SCHEMBL10339460 | 0.75 | HDAC1 (0.43) | SMN1; SMN2MAPTHDAC1HDAC3HDAC2 | |
| SCHEMBL9566457 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTHDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2223566-A | — | — | None | — | — | JP | disclosed |
| JP-H02223566-A | 2-AMINO-1,3,5-TRIAZINE DERIVATIVE AND ANTIULCER AGENT CONTAINING THE SAME DERIVATIVE AS ACTIVE INGREDIENT | TSUMURA & CO | 1990-09-05 | — | — | JP | disclosed |