Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 1.00 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036250 | 0.84 | DYRK1A (0.73) | DYRK1ALIMK1KDM4EALDH1A1POLB | |
| SCHEMBL7130469 | 0.79 | DYRK1A (0.66) | DYRK1ALIMK1KDM4EALDH1A1POLB | |
| SCHEMBL13780833 | 0.79 | DYRK1A (0.66) | DYRK1ALIMK1KDM4EALDH1A1POLB | |
| SCHEMBL30996388 | 0.79 | DYRK1A (0.66) | DYRK1ALIMK1KDM4EALDH1A1BCHE | |
| SCHEMBL13780834 | 0.79 | DYRK1A (0.66) | DYRK1ALIMK1KDM4EALDH1A1POLB | |
| SCHEMBL17705958 | 0.73 | DYRK1A (0.58) | DYRK1AKDM4EALDH1A1POLBBCHE | |
| SCHEMBL7049426 | 0.72 | BCHE (0.65) | DYRK1AKDM4EALDH1A1POLBBCHE | |
| Hydrochloric Acid SCHEMBL8059101 | 0.71 | BCHE (0.63) | DYRK1AKDM4EALDH1A1POLBBCHE | |
| SCHEMBL15759147 | 0.70 | DYRK1A (0.54) | DYRK1AKDM4EALDH1A1POLBBCHE | |
| SCHEMBL9837155 | 0.70 | DYRK1A (0.54) | DYRK1AKDM4EALDH1A1POLBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2221262-A | — | — | None | — | — | JP | disclosed |
| JP-H02221262-A | 4-SUBSTITUTED-BENZO ( H ) QUINAZOLINE DERIVATIVE, 4-SUBSTITUTED-BENZO ( 6,7 ) CYCLOHEPTA ( 1,2-D ) PYRIMIDINE DERIVATIVE AND PLATELET COAGULATION INHIBITOR CONTAINING THE SAME DERIVATIVES AS ACTIVE COMPONENT | NAKAYAMA TAIJI | 1990-09-04 | — | — | JP | disclosed |