SCHEMBL10340409

SCHEMBL10340409

C=CC(C=CC)OC(C)=O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
GALR3 O60755 1/20 0.32
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10340407 1.00 TSHR (0.37) TSHRGALR3MAPTBLMSMN1; SMN2
SCHEMBL3503019 0.84
SCHEMBL27538977 0.82 ALDH1A1 (0.37) TSHRALDH1A1
SCHEMBL1633305 0.79 TSHR (0.31) TSHR
SCHEMBL1633303 0.79 TSHR (0.31) TSHR
SCHEMBL7059950 0.77
SCHEMBL3237622 0.75
SCHEMBL3237619 0.75
SCHEMBL2778945 0.72 TSHR (0.43) TSHRGALR3MAPTBLMSMN1; SMN2
SCHEMBL1326711 0.72 TSHR (0.43) TSHRGALR3MAPTBLMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0254091-B1 METHOD FOR THE PRODUCTION OF 1-ACETOXY-2,4-HEXADIEN BASF Aktiengesellschaft (DE) 1990-02-07 EP disclosed
EP-0254091-A1 Method for the production of 1-acetoxy-2,4-hexadien BASF Aktiengesellschaft (DE) 1988-01-27 EP disclosed