Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19103511 | 0.88 | HTT (0.61) | HTTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL13766911 | 0.88 | HTT (0.58) | HTTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL798337 | 0.87 | ALDH1A1 (0.73) | HTTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL10340550 | 0.86 | HTT (0.65) | HTTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL11128807 | 0.86 | HTT (0.80) | HTTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL31117178 | 0.86 | HTT (0.80) | HTTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL27273816 | 0.85 | HTT (0.58) | HTTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL10340687 | 0.84 | HTT (0.57) | HTTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL6052432 | 0.79 | ALDH1A1 (0.59) | HTTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL23400827 | 0.78 | NPC1 (0.50) | HTTALDH1A1HPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177242-B1 | POLLEN FORMATION INHIBITING PYRAZOLES | ELI LILLY AND COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4775409-A | PREVENTING POLLEN FORMATION | ELI LILLY AND COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
| US-4666504-A | HYBRIDS | ELI LILLY AND COMPANY (US) | 1987-05-19 | — | — | US | disclosed |
| EP-0177242-A2 | Pollen formation inhibiting pyrazoles | ELI LILLY AND COMPANY (US) | 1986-04-09 | — | — | EP | disclosed |