Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 13/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341273 | 0.96 | HDAC3 (0.45) | OPRK1HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL10341275 | 0.95 | OPRK1 (0.43) | OPRK1HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL10341266 | 0.91 | HDAC3 (0.44) | OPRK1HDAC3HDAC11HDAC6HDAC1 | |
| Glaspimod SCHEMBL609834 | 0.91 | FOLH1 (0.48) | OPRK1HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL11246319 | 0.91 | OPRK1 (0.49) | OPRK1HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL10341270 | 0.91 | HDAC3 (0.42) | OPRK1HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL10341274 | 0.90 | HDAC3 (0.42) | OPRK1HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL11104820 | 0.84 | HDAC3 (0.48) | OPRK1HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL29829129 | 0.83 | CXCR4 (0.40) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL23300537 | 0.81 | HDAC3 (0.48) | HDAC3HDAC11HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112656-B1 | PEPTIDE COMPOUNDS | NYCOMED AS (NO) | 1990-03-07 | — | — | EP | claimed |
| US-4499081-A | INHIBITS MYELOPOIETIC SYSTEM OF HUMANS AND ANIMALS | NYEGAARD & CO A/S (NO) | 1985-02-12 | — | — | US | claimed |
| EP-0112656-A2 | Peptide compounds | NYCOMED AS (NO) | 1984-07-04 | — | — | EP | claimed |
| EP-0112656-B1 | PEPTIDE COMPOUNDS | NYCOMED AS (NO) | 1990-03-07 | — | — | EP | disclosed |
| US-4499081-A | INHIBITS MYELOPOIETIC SYSTEM OF HUMANS AND ANIMALS | NYEGAARD & CO A/S (NO) | 1985-02-12 | — | — | US | disclosed |
| EP-0112656-A2 | Peptide compounds | NYCOMED AS (NO) | 1984-07-04 | — | — | EP | disclosed |