Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341808 | 0.92 | MAPT (0.58) | LMNAMAPTKMT2AMEN1TP53 | |
| SCHEMBL10341875 | 0.91 | MAPT (0.54) | LMNAMAPTKMT2AMEN1TP53 | |
| SCHEMBL10341988 | 0.91 | KMT2A (0.55) | LMNAMAPTKMT2AMEN1TP53 | |
| SCHEMBL10341800 | 0.89 | MAPT (0.55) | LMNAMAPTKMT2AMEN1TP53 | |
| SCHEMBL10341841 | 0.89 | MAPT (0.58) | LMNAMAPTKMT2AMEN1TP53 | |
| SCHEMBL10341812 | 0.86 | MAPT (0.52) | LMNAMAPTKMT2AMEN1TP53 | |
| SCHEMBL10868001 | 0.81 | LMNA (0.42) | LMNAMAPTKMT2AMEN1TP53 | |
| SCHEMBL11433007 | 0.81 | MAPT (0.60) | LMNAMAPTKMT2AMEN1TP53 | |
| SCHEMBL10955599 | 0.80 | MAPT (0.66) | LMNAMAPTKMT2AMEN1TP53 | |
| SCHEMBL10868003 | 0.79 | MAPT (0.45) | LMNAMAPTKMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181284-B1 | AMINO ACID ESTERS | SANDOZ AG (CH) | 1990-02-07 | — | — | EP | disclosed |
| EP-0181284-A1 | Amino acid esters | SANDOZ AG (CH) | 1986-05-14 | — | — | EP | disclosed |