Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.51 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2681577 | 0.87 | MEN1 (0.44) | SRPK1KDRSRPK2SRPK3RXFP1 | |
| SCHEMBL1035169 | 0.86 | HTR1F (0.48) | P2RY14 | |
| SCHEMBL1846198 | 0.82 | P2RY14 (0.49) | P2RY14CRACR2A | |
| SCHEMBL14453579 | 0.75 | BRAF (0.65) | SRPK1KDRSRPK2SRPK3RXFP1 | |
| SCHEMBL1027433 | 0.75 | KDR (0.58) | SRPK1KDRSRPK2SRPK3RXFP1 | |
| SCHEMBL20448230 | 0.74 | SRPK1 (0.44) | SRPK1KDRSRPK2SRPK3RXFP1 | |
| SCHEMBL14453684 | 0.74 | PTGS1 (0.61) | SRPK1KDRSRPK2SRPK3RXFP1 | |
| SCHEMBL1031737 | 0.73 | HIF1A (0.51) | SRPK1KDRSRPK2SRPK3HTR2C | |
| SCHEMBL2681631 | 0.73 | MAP4K1 (0.46) | — | |
| SCHEMBL1033839 | 0.72 | MEN1 (0.47) | SRPK1KDRSRPK2SRPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011003684-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-01-13 | — | — | WO | disclosed |