SCHEMBL10342102

SCHEMBL10342102

CC(C)c1cccc(C(N)N)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.48
HDAC4 P56524 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
ALDH1A1 P00352 2/20 0.47
ALOX12 P18054 2/20 0.47
HTT P42858 2/20 0.47
KDM4E B2RXH2 2/20 0.47
MDM4 O15151 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPT P10636 1/20 0.47
TYR P14679 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
CA5A P35218 1/20 0.47
MDM2 Q00987 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL374780 0.87 HDAC4 (0.56) HDAC4HDAC8ALDH1A1ALOX12HTT
SCHEMBL14332317 0.87 F2 (0.61) F2CYP3A4ADRB1MIFHTR2A
SCHEMBL14975715 0.85 HDAC4 (0.47) HDAC4HDAC8ALDH1A1ALOX12HTT
SCHEMBL14847092 0.85 HDAC4 (0.47) HDAC4HDAC8ALDH1A1ALOX12HTT
Benzene SCHEMBL7084450 0.84 HDAC4 (0.54) HDAC4HDAC8ALDH1A1ALOX12HTT
SCHEMBL11036540 0.84 HDAC4 (0.54) HDAC4HDAC8ALDH1A1ALOX12HTT
SCHEMBL19031518 0.84 KDM4E (0.54) HDAC4HDAC8ALDH1A1ALOX12HTT
SCHEMBL31122172 0.84 HDAC4 (0.54) HDAC4HDAC8ALDH1A1ALOX12HTT
Water SCHEMBL9322811 0.84 HDAC4 (0.54) HDAC4HDAC8ALDH1A1ALOX12HTT
Hydrochloric Acid SCHEMBL28429663 0.84 HDAC4 (0.54) HDAC4HDAC8ALDH1A1ALOX12HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0177916-B1 MONO-TERTIARY-ALKYLATED TOLUENEDIAMINE AND DERIVATIVES AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-04-11 EP disclosed
US-4745223-A CHAIN EXTENDERS FOR POLYUREAS AND POLYURETHANES AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-05-17 US disclosed
EP-0177916-A1 Mono-tertiary-alkylated toluenediamine and derivatives AIR PRODUCTS AND CHEMICALS, INC. (US) 1986-04-16 EP disclosed