Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034240 | 0.86 | EGLN2 (0.56) | EGLN2EGLN1 | |
| SCHEMBL522013 | 0.84 | EGLN1 (0.66) | EGLN2EGLN1 | |
| SCHEMBL521838 | 0.81 | EGLN2 (0.46) | EGLN2EGLN1 | |
| SCHEMBL6908613 | 0.76 | EGLN2 (0.54) | EGLN2EGLN1 | |
| SCHEMBL8141668 | 0.75 | EGLN2 (0.48) | EGLN2 | |
| SCHEMBL5075176 | 0.75 | EGLN1 (0.66) | EGLN2EGLN1 | |
| SCHEMBL523424 | 0.75 | EGLN1 (0.78) | EGLN2EGLN1 | |
| SCHEMBL522977 | 0.75 | EGLN1 (0.62) | EGLN2EGLN1 | |
| SCHEMBL21361727 | 0.75 | EGLN1 (0.70) | EGLN2EGLN1 | |
| SCHEMBL29726498 | 0.75 | EGLN1 (0.70) | EGLN2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2357175-A1 | isoquinoline derivatives AND THEIR USE IN INCREASING ENDOGENEOUS ERYTHROPOIETIN | Fibrogen, Inc. (US) | 2011-08-17 | — | — | EP | disclosed |
| EP-1644336-B1 | NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND THEIR USE IN INCREASING ENDOGENEOUS ERYTHROPOIETIN | FIBROGEN INC (US) | 2011-01-19 | — | — | EP | disclosed |