⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16107026 | 0.97 | GAA (0.39) | — | |
| Hydrochloric Acid SCHEMBL6045203 | 0.97 | — | — | |
| SCHEMBL3686600 | 0.80 | CA1 (0.39) | — | |
| SCHEMBL25139840 | 0.80 | GAA (0.34) | — | |
| SCHEMBL21638038 | 0.80 | GAA (0.34) | — | |
| SCHEMBL7524063 | 0.79 | FFAR2 (0.37) | — | |
| SCHEMBL13337074 | 0.78 | GAA (0.33) | — | |
| SCHEMBL768028 | 0.76 | — | — | |
| SCHEMBL3313676 | 0.76 | — | — | |
| SCHEMBL146291 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3534 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630491-B2 | Production of 2,2,4,4-tetramethylcyclobutane-1,3-diol from secondary alcohols and 2,2,4,4-tetramethylcyclobutanedione using homogeneous catalysts | EASTMAN CHEMICAL COMPANY (US) | 2026-05-19 | — | — | US | claimed |
| US-20260014166-A1 | NOVEL USES OF DUAL NK-1 /NK-3 RECEPTOR ANTAGONISTS FOR TREATING SEX-HORMONE DISEASES | KaNDy Therapeutics Limited (GB) | 2026-01-15 | — | — | US | claimed |
| CN-119744120-A | Perilla oil for harmonizing unique flavor and nut taste of perilla seeds and preparation method thereof | CJ第一制糖株式会社 | 2025-04-01 | — | — | CN | claimed |
| EP-4255881-B1 | PRODUCTION OF 2,2,4, 4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM SECONDARY ALCOHOLS AND 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIONE USING HOMOGENEOUS CATALYSTS | EASTMAN CHEM CO (US) | 2024-12-18 | — | — | EP | claimed |
| US-12129332-B2 | Self-supporting photochromic polyurethane film, method of manufacturing the film, article comprising said film | NANOGATE SE (DE) | 2024-10-29 | — | — | US | claimed |
| CN-113840820-B | Phthalazinone compounds and uses thereof | ST制药株式会社 | 2024-05-03 | — | — | CN | claimed |
| US-20230406792-A1 | PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1,3-DIOL FROM SECONDARY ALCOHOLS AND 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIONE USING HOMOGENEOUS CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2023-12-21 | — | — | US | claimed |
| CN-111819176-B | 4-azaindole compounds | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | claimed |
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | claimed |
| EP-4255881-A1 | PRODUCTION OF 2,2,4, 4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM SECONDARY ALCOHOLS AND 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIONE USING HOMOGENEOUS CATALYSTS | Eastman Chemical Company (US) | 2023-10-11 | — | — | EP | claimed |
| CN-1056605-C | Compounds as selective antagonists of human tachykinin III receptor and uses thereof | SANOFI CORP (FR) | 2000-09-20 | — | — | CN | claimed |
| WO-2000040576-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-13 | — | — | WO | claimed |
| WO-2000021364-A2 | A NATURAL AND SAFE ALTERNATIVE TO FUNGICIDES, BACTERIOCIDES, NEMATICIDES AND INSECTICIDES FOR PLANT PROTECTION AND AGAINST HOUSEHOLD PESTS | AUBURN UNIVERSITY (US) | 2000-04-20 | — | — | WO | claimed |
| US-5942523-A | NOVEL PIPERIDINE DERIVATIVES WHOSE SPECIFIC STRUCTURE INCLUDES AT POSITION 1 AN ALKYL CHAIN HAVING A 3,4-DICHLOROPHENYL GROUP ATTACHED; HIGH SELECTIVITY TO THE NK3 RECEPTOR; UNIT DOSAGE FORM; TREATING PSYCHIATRIC DISEASES | SANOFI (FR) | 1999-08-24 | — | — | US | claimed |
| EP-0779888-B1 | PYRIMIDO [5,4-D]PYRIMIDINES, DRUGS CONTAINING THESE COMPOUNDS, THEIR USE, AND PROCESS FOR PREPARING THEM | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-04-28 | — | — | EP | claimed |
| US-5707989-A | ANTITUMOR AGENTS, INHIBITING SIGNAL TRANSDUCTION MEDIATED BY TYROSINE KINASES | DR. KARL THOMAE GMBH (DE) | 1998-01-13 | — | — | US | claimed |
| CN-1128756-A | Compounds as selective antagonists of the human tachykinin III receptor and uses thereof | SANOFI CORP (FR) | 1996-08-14 | — | — | CN | claimed |
| EP-0673928-A1 | Novel N-(3,4-dichlorophenyl-propyl)-piperidine derivatives as selective human NK3-receptor antagonists | SANOFI (FR) | 1995-09-27 | — | — | EP | claimed |
| US-5103055-A | Water-promoted synthesis of amides from nitriles and alcohols | THE STANDARD OIL COMPANY (US) | 1992-04-07 | — | — | US | claimed |
| US-4268510-A | DEMETHANIZATION, METABOLISM, RUMEN | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-05-19 | — | — | US | claimed |