Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 14/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10343908 | 0.91 | GCGR (0.42) | GCGRALDH1A1KDM4ECYP19A1 | |
| SCHEMBL10989730 | 0.88 | GCGR (0.41) | GCGRNPC1HPGDMAPK1HTT | |
| SCHEMBL10344205 | 0.86 | GCGR (0.37) | GCGR | |
| SCHEMBL8165780 | 0.83 | NPC1 (0.39) | GCGRNPC1HPGDMAPK1HTT | |
| SCHEMBL27843325 | 0.78 | ESR1 (0.39) | GCGRHTTRAB9ANPSR1HCAR2 | |
| SCHEMBL522840 | 0.77 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL9503180 | 0.76 | NPC1 (0.35) | GCGRNPC1HPGDMAPK1HTT | |
| SCHEMBL5592696 | 0.76 | HPGD (0.45) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL5589084 | 0.76 | HPGD (0.41) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL5590008 | 0.76 | HPGD (0.41) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221635-B1 | FLUORO ALCOHOLS AND INSECTICIDAL ESTERS THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-03-14 | — | — | EP | disclosed |
| US-4714790-A | Fluoro alcohols and insecticidal esters thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-12-22 | — | — | US | disclosed |
| EP-0221635-A1 | Fluoro alcohols and insecticidal esters thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-05-13 | — | — | EP | disclosed |