SCHEMBL522840

SCHEMBL522840

OCc1c(F)c(F)c(F)c(F)c1CO

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.30
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536295 0.92 POLB (0.32) SMN1; SMN2DRD4
SCHEMBL522960 0.89 POLB (0.32)
SCHEMBL522934 0.88 POLB (0.33) SMN1; SMN2DRD4
SCHEMBL10344204 0.87 GCGR (0.34)
SCHEMBL28913708 0.81
SCHEMBL10344205 0.81 GCGR (0.37)
SCHEMBL24834493 0.79 POLB (0.31)
SCHEMBL10343892 0.79 TSHR (0.30)
SCHEMBL10343907 0.79 GABRA1 (0.32)
SCHEMBL9340382 0.79 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1322584-B1 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL SHOWA DENKO KK (JP) 2004-11-24 EP claimed
EP-3882235-B1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND UNIV KOBE NAT UNIV CORP (JP) 2025-01-22 EP disclosed
US-12060312-B2 Production method for isocyanate compound NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2024-08-13 US disclosed
US-20220002234-A1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2022-01-06 US disclosed
EP-3882235-A1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND National University Corporation Kobe University (JP) 2021-09-22 EP disclosed
US-10147553-B2 Hydrophilic conjugated polymers, and methods of preparation and use thereof UNIVERSITY OF MASSACHUSETTS (US) 2018-12-04 US disclosed
US-20170263385-A1 HYDROPHILIC CONJUGATED POLYMERS, AND METHODS OF PREPARATION AND USE THEREOF NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2017-09-14 US disclosed
EP-2415741-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND Sumitomo Chemical Company, Limited (JP) 2012-02-08 EP disclosed
EP-2415742-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR Sumitomo Chemical Company, Limited (JP) 2012-02-08 EP disclosed
US-20120029195-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-02 US disclosed
EP-1322584-A2 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL Showa Denko K.K. (JP) 2003-07-02 EP disclosed
EP-1299343-A1 PRODUCTION METHOD FOR BENZENEDIMETHANOL COMPOUND Showa Denko K.K. (JP) 2003-04-09 EP disclosed
WO-2002026678-A2 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL SHOWA DENKO K.K. (JP) 2002-04-04 WO disclosed
WO-2002002504-A1 PRODUCTION METHOD FOR BENZENEDIMETHANOL COMPOUND SHOWA DENKO K.K. (JP) 2002-01-10 WO disclosed
JP-2001158754-A METHOD FOR PRODUCING TETRAFLUOROBENZENEDIMETHANOL SHOWA DENKO KK 2001-06-12 JP disclosed
EP-0767770-A1 METHOD FOR PREPARING ALKYLATING AGENTS AND THEIR USE FOR ALKYLATING CYCLIC UREAS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1997-04-16 EP disclosed
WO-1996000708-A1 METHOD FOR PREPARING ALKYLATING AGENTS AND THEIR USE FOR ALKYLATING CYCLIC UREAS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-01-11 WO disclosed
US-4217302-A INSECTICIDES, MITICIDES ZOECON CORPORATION (US) 1980-08-12 US disclosed
US-4189598-A INSECTICIDES., MITICIDE ZOECON CORPORATION (US) 1980-02-19 US disclosed
US-4178293-A Isoindolinyl derivatives ZOECON CORPORATION (US) 1979-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12060312-B2 Production method for isocyanate compound IDH2, CBR3, IDH3A SMN1; SMN2 4459/4885DRD4 927/4885
US-20220002234-A1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND IDH2, CBR3, IDH3A SMN1; SMN2 4459/4885DRD4 927/4885
US-20120029195-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR ADH1A, ADH1C, ADH5 SMN1; SMN2 4872/4885DRD4 848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.