SCHEMBL10344229

SCHEMBL10344229

CCOC(=O)OC1CCC(OC(=O)OCC)C1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
SOAT1 P35610 1/20 0.48
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GAA P10253 2/20 0.37
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
PPM1B O75688 1/20 0.35
PTPN1 P18031 1/20 0.35
PPP1CC P36873 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
ADRA1A P35348 1/20 0.35
CHRNA4 P43681 1/20 0.35
HTR3A P46098 1/20 0.35
KCNH2 Q12809 1/20 0.35
TRPA1 O75762 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2423736 0.94 ALDH1A1 (0.46) ALDH1A1SOAT1LMNAHSD17B10GAA
SCHEMBL1079924 0.93 ALDH1A1 (0.55) ALDH1A1SOAT1LMNAHSD17B10GAA
SCHEMBL4640870 0.91
SCHEMBL1078049 0.91 ALDH1A1 (0.57) ALDH1A1SOAT1LMNAHSD17B10GAA
SCHEMBL1079453 0.87 ALDH1A1 (0.40) ALDH1A1SOAT1GAAMGAMSI
SCHEMBL1079266 0.87 EPHX1 (0.50) ALDH1A1SOAT1HSD17B10ALOX15EPHX1
SCHEMBL1079728 0.86 ALDH1A1 (0.43) ALDH1A1SOAT1LMNAHSD17B10GAA
SCHEMBL1078514 0.85 ALDH1A1 (0.46) ALDH1A1SOAT1LMNAHSD17B10GAA
SCHEMBL305155 0.84 ALDH1A1 (0.50) ALDH1A1SOAT1LMNAHSD17B10ALOX15
SCHEMBL8375449 0.84 ALDH1A1 (0.50) ALDH1A1SOAT1LMNAHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012096404-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-19 WO disclosed