SCHEMBL10344348

SCHEMBL10344348

CCCCOC(=O)c1ccc(OC(=O)c2ccc(C(=O)Oc3ccc(C(=O)OCCCC)cc3)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.72
CYP1A2 P05177 3/20 0.72
CYP2C19 P33261 3/20 0.72
TSHR P16473 2/20 0.72
CYP2D6 P10635 2/20 0.72
ESR1 P03372 1/20 0.72
MAPK1 P28482 1/20 0.72
NR1H2 P55055 1/20 0.72
RNASEL Q05823 1/20 0.72
SMN1; SMN2 Q16637 1/20 0.72
CYP3A4 P08684 2/20 0.70
CYP2C9 P11712 2/20 0.70
PDE4D Q08499 1/20 0.70
MAPT P10636 5/20 0.67
HPGD P15428 2/20 0.67
ALDH1A1 P00352 2/20 0.67
KMT2A Q03164 2/20 0.67
MEN1 O00255 1/20 0.67
STS P08842 7/20 0.65
RECQL P46063 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19373810 0.97 MAPT (0.71) LMNACYP1A2CYP2C19TSHRCYP2D6
SCHEMBL19373817 0.95 MAPT (0.74) LMNACYP1A2CYP2C19TSHRCYP2D6
SCHEMBL19373812 0.95 MAPT (0.74) LMNACYP1A2CYP2C19TSHRCYP2D6
SCHEMBL19373809 0.95 MAPT (0.74) LMNACYP1A2CYP2C19TSHRCYP2D6
SCHEMBL19373815 0.95 MAPT (0.74) LMNACYP1A2CYP2C19TSHRCYP2D6
SCHEMBL10344104 0.95 MAPT (0.74) LMNACYP1A2CYP2C19TSHRCYP2D6
SCHEMBL19373811 0.95 MAPT (0.74) LMNACYP1A2CYP2C19TSHRCYP2D6
SCHEMBL19373805 0.95 MAPT (0.74) LMNACYP1A2CYP2C19TSHRCYP2D6
SCHEMBL27922198 0.94 LMNA (0.64) LMNACYP1A2CYP2C19TSHRCYP2D6
SCHEMBL27741024 0.94 ESR1 (0.84) LMNACYP1A2CYP2C19TSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170269487-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR MANUFACTURING SAME AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2017-09-21 US disclosed
US-20170269487-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR MANUFACTURING SAME AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2017-09-21 US disclosed
EP-0181404-B1 PHTHALATE COMPOUNDS Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1990-02-07 EP disclosed
EP-0181404-A1 PHTHALATE COMPOUNDS Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1986-05-21 EP disclosed