Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 12/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 12/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693383 | 0.99 | LTB4R (0.40) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL10689515 | 0.92 | LTB4R (0.41) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL10344546 | 0.92 | LTB4R (0.41) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL10344328 | 0.91 | LTB4R (0.40) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL10344174 | 0.86 | PPARG (0.56) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL10344478 | 0.85 | PPARG (0.56) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL10735645 | 0.84 | LTB4R (0.41) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL10344475 | 0.84 | LTB4R (0.44) | LTB4RLTB4R2ALDH1A1AKT1KDM4E | |
| SCHEMBL10738497 | 0.79 | AKT1 (0.36) | LTB4RLTB4R2AKT1 | |
| SCHEMBL10694129 | 0.77 | LTB4R (0.46) | LTB4RLTB4R2ALDH1A1AKT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261254-B1 | 3,4-DIHYDRO-4-OXO-2H-1-BENZOPYRANYLOXY ALKANOIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1990-02-07 | — | — | EP | disclosed |
| EP-0261254-A1 | 3,4-Dihydro-4-oxo-2H-1-benzopyranyloxy alkanoic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-03-30 | — | — | EP | disclosed |
| US-4650812-A | ANTIALLERGY | HOFFMANN-LA ROCHE INC. (US) | 1987-03-17 | — | — | US | disclosed |