SCHEMBL1034440

SCHEMBL1034440

C=C(C)c1ccccc1.N#CC=CC=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.46
MAOB P27338 2/20 0.44
MCL1 Q07820 1/20 0.38
HDAC3 O15379 2/20 0.36
HDAC4 P56524 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC7 Q8WUI4 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC10 Q969S8 2/20 0.36
HDAC11 Q96DB2 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
HDAC9 Q9UKV0 2/20 0.36
HDAC5 Q9UQL6 2/20 0.36
GLA P06280 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 6/20 0.35
ALDH1A1 P00352 4/20 0.35
TRPA1 O75762 1/20 0.35
ALOX5 P09917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butadiene SCHEMBL29023919 0.96 CYP3A4 (0.43) CYP3A4MAOBMCL1HDAC3HDAC4
Methacrylic Acid SCHEMBL1035064 0.93 CYP3A4 (0.41) CYP3A4MAOBMCL1HDAC3HDAC4
SCHEMBL11130616 0.87 LMNA (0.45) CYP3A4MAOBMCL1HDAC3HDAC4
SCHEMBL11421186 0.87 CYP3A4 (0.49) CYP3A4MAOBMCL1HDAC3HDAC4
SCHEMBL6013130 0.86 CYP3A4 (0.47) CYP3A4MAOBMCL1HDAC3HDAC4
Methacrylic Acid SCHEMBL6906597 0.84 CYP3A4 (0.46) CYP3A4MAOBMCL1HDAC3HDAC4
Methacrylic Acid SCHEMBL437865 0.84 CYP3A4 (0.46) CYP3A4MAOBMCL1HDAC3HDAC4
1,1-Dichloroethene SCHEMBL9357233 0.83 MAOB (0.50) CYP3A4MAOBMCL1HDAC3HDAC4
Methacrylic Acid SCHEMBL28068002 0.83 CYP3A4 (0.45) CYP3A4MAOBMCL1HDAC3HDAC4
Ethylene SCHEMBL7925748 0.83 MAOB (0.58) CYP3A4MAOBMCL1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2111427-B1 LOW SURFACE GLOSS STYRENE RESIN COMPOSITION, AND LOW SURFACE GLOSS SHEET AND COMPOSITE ARTICLE THEREFROM LG CHEMICAL LTD (KR) 2014-04-30 EP claimed
EP-1802447-B1 METHOD FOR REDUCING STRINGINESS OF A RESINOUS COMPOSITION DURING HOT PLATE WELDING SABIC INNOVATIVE PLASTICS IP (NL) 2011-01-26 EP claimed
EP-0186926-B1 METHOD FOR THE PREPARATION OF GRAFT COPOLYMERS BY EMULSION COPOLYMERIZATION MONTEDIPE S.r.l. (IT) 1991-01-16 EP claimed
CN-114014985-B Alpha-methylstyrene copolymer and preparation method and application thereof 万华化学(四川)有限公司 2023-09-19 CN disclosed
CN-114014985-A Alpha-methylstyrene copolymer and preparation method and application thereof 万华化学(四川)有限公司 2022-02-08 CN disclosed
CN-112480583-B Blend optical film with thermodynamic stability and preparation method thereof 聚纶材料科技(深圳)有限公司 2021-10-26 CN disclosed
EP-3858915-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED PRODUCT USING SAME Lotte Chemical Corporation (KR) 2021-08-04 EP disclosed
CN-112480583-A Blend optical film with thermodynamic stability and preparation method thereof 聚纶材料科技(深圳)有限公司 2021-03-12 CN disclosed
EP-2865714-B1 Thermoplastic resin composition having excellent colorability and mechanical and physical properties LOTTE ADVANCED MAT CO LTD (KR) 2018-10-24 EP disclosed
CN-105452367-A Soft thermoplastic resin composition KANEKA CORP 2016-03-30 CN disclosed
CN-105452368-A Soft thermoplastic resin composition KANEKA CORP 2016-03-30 CN disclosed
CN-1118512-C ABS resin molded article having excellent impact resistance after coating QIMEI IND CO LTD (CN) 2003-08-20 CN disclosed
CN-1345354-A Moulding materials for use in motor vehicle interiors BASF AG (DE) 2002-04-17 CN disclosed
CN-1243140-A ABS resin molded article having excellent impact resistance after coating QIMEI IND CO LTD (CN) 2000-02-02 CN disclosed
CN-1198451-A Laminated sheet material or laminated film and moulded products thereof BASF AG (DE) 1998-11-11 CN disclosed
US-4692295-A USING A LOWER STRETCHING FORCE BY INCLUDING A HIGH MOLECULAR WEIGHT ADDITIVE ADDITION POLYMER PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1987-09-08 US disclosed
US-4243769-A NITRILE POLYMER, HYDROXY OR ESTER POLYMER, ACID NATIONAL DISTILLERS AND CHEMICAL CORP. (US) 1981-01-06 US disclosed
US-4145377-A MOLDING MATERIALS GENERAL ELECTRIC COMPANY (US) 1979-03-20 US disclosed
US-3994856-A HEAT RESISTANCE GENERAL ELECTRIC COMPANY (US) 1976-11-30 US disclosed
US-3970718-A Method of producing polymer compositions based on chlorinated polyethylene SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-07-20 US disclosed