Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19946014 | 0.76 | ESR1 (0.60) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL874357 | 0.75 | CYP2D6 (0.39) | LMNACYP2D6TSHRSRC | |
| SCHEMBL11186081 | 0.75 | ESR1 (0.46) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL9181782 | 0.75 | ESR1 (0.46) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL6875459 | 0.73 | ESR1 (0.44) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL349497 | 0.71 | ESR1 (0.43) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL11781695 | 0.71 | ESR1 (0.43) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL29012807 | 0.71 | ESR1 (0.43) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL11243676 | 0.71 | ESR1 (0.43) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL582044 | 0.71 | ESR1 (0.54) | ESR1ESR2PDCD1CD274ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360437-A1 | Biocidal polylamine-amides | BTG INTERNATIONAL LIMITED (GB) | 1990-03-28 | — | — | EP | disclosed |