Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349497 | 1.00 | ESR1 (0.43) | ESR1ESR2PDCD1CD274TAAR1 | |
| SCHEMBL29012807 | 1.00 | ESR1 (0.43) | ESR1ESR2PDCD1CD274TAAR1 | |
| SCHEMBL9665245 | 0.78 | MAPT (0.40) | HIF1ATSHRALOX15KDM4ETDP1 | |
| SCHEMBL10403346 | 0.76 | ESR1 (0.48) | ESR1ESR2PDCD1CD274TAAR1 | |
| SCHEMBL11301520 | 0.76 | ESR1 (0.60) | ESR1ESR2PDCD1CD274TAAR1 | |
| SCHEMBL11015372 | 0.76 | ADRB2 (0.50) | HIF1ANFKB1TSHRTDP1CYP3A4 | |
| SCHEMBL7192536 | 0.76 | TDP1 (0.50) | TAAR1HIF1ANFKB1TSHRALOX15 | |
| SCHEMBL1036920 | 0.75 | DPP4 (0.50) | TAAR1HIF1AKDM4ELMNACYP2D6 | |
| SCHEMBL11186081 | 0.75 | ESR1 (0.46) | ESR1ESR2PDCD1CD274TAAR1 | |
| SCHEMBL3758015 | 0.75 | DPP4 (0.50) | TAAR1HIF1AKDM4ELMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053539-A1 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1982-06-09 | — | — | EP | disclosed |