SCHEMBL10344732

SCHEMBL10344732

O=C(O)c1cccc(Br)c1.O=S(=O)(Cl)Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.55
MRGPRX4 Q96LA9 1/20 0.50
FLT1 P17948 1/20 0.49
FLT4 P35916 1/20 0.49
KDR P35968 1/20 0.49
ALDH1A1 P00352 1/20 0.49
TP53 P04637 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA6 P23280 1/20 0.48
CA9 Q16790 1/20 0.48
MTOR P42345 1/20 0.48
GRIK1 P39086 1/20 0.47
HPGD P15428 3/20 0.46
C1S P09871 1/20 0.46
KMO O15229 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29537403 0.90 PARP1 (0.65) PARP1MRGPRX4ALDH1A1TP53CA12
SCHEMBL5023 0.90 PARP1 (0.65) PARP1MRGPRX4ALDH1A1TP53CA12
SCHEMBL11539652 0.88 PARP1 (0.63) PARP1MRGPRX4ALDH1A1TP53CA12
Hydrochloric Acid SCHEMBL698593 0.88 PARP1 (0.63) PARP1MRGPRX4ALDH1A1TP53CA12
Ethane SCHEMBL17336854 0.86 PARP1 (0.61) PARP1MRGPRX4ALDH1A1TP53CA12
1,2-Dichloroethane SCHEMBL27913129 0.85 PARP1 (0.55) PARP1MRGPRX4ALDH1A1TP53CA12
Boric Acid SCHEMBL29232610 0.81 PARP1 (0.55) PARP1MRGPRX4ALDH1A1TP53CA12
Isophthalic Acid SCHEMBL28667980 0.79 CA12 (0.56) PARP1MRGPRX4TP53CA12CA1
Pyridine SCHEMBL28674978 0.79 PARP1 (0.53) PARP1MRGPRX4ALDH1A1TP53CA12
SCHEMBL27480599 0.79 POLB (0.54) PARP1FLT1FLT4KDRCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0176325-B1 LIGHT SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1990-04-04 EP disclosed
US-4670375-A USE OF MONODISPERSED SILVER HALIDE GRAINS AND INCREASED CONCENTRATION IN EMULSION LAYER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-06-02 US disclosed
EP-0176325-A2 Light sensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-04-02 EP disclosed