SCHEMBL11539652

SCHEMBL11539652

O=C(O)c1cccc(Br)c1.O=C(O)c1cccc(Br)c1.O=C(O)c1cccc(Br)c1.O=C(O)c1cccc(Br)c1.[Pb]

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.63
MRGPRX4 Q96LA9 1/20 0.56
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA6 P23280 1/20 0.56
CA9 Q16790 1/20 0.56
ALDH1A1 P00352 1/20 0.55
TP53 P04637 1/20 0.55
MTOR P42345 1/20 0.53
HPGD P15428 3/20 0.52
C1S P09871 1/20 0.52
KMO O15229 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
HSD17B10 Q99714 1/20 0.52
DAO P14920 1/20 0.50
TSHR P16473 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5023 0.98 PARP1 (0.65) PARP1MRGPRX4CA12CA1CA2
SCHEMBL29537403 0.98 PARP1 (0.65) PARP1MRGPRX4CA12CA1CA2
Hydrochloric Acid SCHEMBL698593 0.95 PARP1 (0.63) PARP1MRGPRX4CA12CA1CA2
Ethane SCHEMBL17336854 0.93 PARP1 (0.61) PARP1MRGPRX4CA12CA1CA2
1,2-Dichloroethane SCHEMBL27913129 0.88 PARP1 (0.55) PARP1MRGPRX4CA12CA1CA2
Boric Acid SCHEMBL29232610 0.88 PARP1 (0.55) PARP1MRGPRX4CA12CA1CA2
SCHEMBL10344732 0.88 PARP1 (0.55) PARP1MRGPRX4CA12CA1CA2
Isophthalic Acid SCHEMBL28667980 0.86 CA12 (0.56) PARP1MRGPRX4CA12CA1CA2
Pyridine SCHEMBL28674978 0.86 PARP1 (0.53) PARP1MRGPRX4CA12CA1CA2
SCHEMBL30014390 0.85 KMO (0.68) PARP1MRGPRX4CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4172832-A Mercaptoalcohols and process for their manufacture CIBA-GEIGY CORPORATION (US) 1979-10-30 US disclosed