SCHEMBL10344874

SCHEMBL10344874

CCOC(=O)CSc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
TTR P02766 1/20 0.61
PPOX P50336 1/20 0.61
FFAR1 O14842 2/20 0.45
GAA P10253 1/20 0.44
ALDH1A1 P00352 5/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
LMNA P02545 4/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 4/20 0.42
HPGD P15428 1/20 0.42
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10928036 0.90 MEN1 (0.58) TDP1MEN1KMT2ATTRPPOX
SCHEMBL11025179 0.89 MEN1 (0.56) TDP1MEN1KMT2ATTRPPOX
SCHEMBL10922561 0.88 MEN1 (0.69) TDP1MEN1KMT2ATTRPPOX
SCHEMBL10964950 0.87 ALDH1A1 (0.48) TDP1MEN1KMT2ATTRPPOX
SCHEMBL10998808 0.86 MEN1 (0.66) TDP1MEN1KMT2ATTRPPOX
SCHEMBL10926702 0.86 MEN1 (0.56) TDP1MEN1KMT2ATTRPPOX
SCHEMBL10980800 0.86 MEN1 (0.61) TDP1MEN1KMT2ATTRPPOX
SCHEMBL10510494 0.85 MEN1 (0.56) TDP1MEN1KMT2ATTRPPOX
SCHEMBL10344875 0.85 MEN1 (0.63) TDP1MEN1KMT2ATTRPPOX
SCHEMBL10378971 0.84 MEN1 (0.61) TDP1MEN1KMT2ATTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4473392-A BROADLEAF PLANTS AMONG CEREALS BASF AKTIENGESELLSCHAFT (DE) 1984-09-25 US claimed
EP-0027915-B1 HERBICIDAL AGENTS BASED ON DIPHENYL ETHERS AND BENZOTHIADIAZINONE DIOXIDES OR PYRIDINOTHIADIAZINONE DIOXIDES, AND THEIR USE BASF Aktiengesellschaft (DE) 1983-05-18 EP claimed
EP-0192111-B1 ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
US-4744812-A HALOGENATED DIPHENYL ETHER BASF AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed
EP-0192111-A1 Iso-ureas, processes for their production and their use as herbicides BASF Aktiengesellschaft (DE) 1986-08-27 EP disclosed
EP-0115808-B1 CYCLOHEXAN-1,3-DIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1986-08-20 EP disclosed
EP-0170203-A2 4H-Pyrido(2,3-d)(1,3)oxazin-4-one derivatives, process for their preparation, and their use for combating undesired vegetation BASF Aktiengesellschaft (DE) 1986-02-05 EP disclosed
EP-0053679-B1 DIPHENYL ETHER, PREPARATION AND USE AS HERBICIDE BASF Aktiengesellschaft (DE) 1986-01-22 EP disclosed
EP-0049398-B1 4H-3,1-BENZOXAZIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1985-03-06 EP disclosed
EP-0053698-B1 5-AMINO-1-PHENYLPYRAZOLE-4-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, HERBICIDES CONTAINING THEM AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1985-01-09 EP disclosed
US-4473392-A BROADLEAF PLANTS AMONG CEREALS BASF AKTIENGESELLSCHAFT (DE) 1984-09-25 US disclosed
EP-0035712-B1 N-ARYL(THIOL) CARBAMATES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATING UNDESIRED PLANT GROWTH BASF Aktiengesellschaft (DE) 1983-02-16 EP disclosed
EP-0056119-A1 Substituted diphenyl ethers, herbicides containing them and their use as herbicides BASF Aktiengesellschaft (DE) 1982-07-21 EP disclosed
EP-0053698-A1 5-Amino-1-phenylpyrazole-4-carboxylic acids, process for their preparation, herbicides containing them and their use as herbicides BASF Aktiengesellschaft (DE) 1982-06-16 EP disclosed
EP-0051155-A1 Use of 2-aryloxy-2-azolylalkanecarbonic amides as herbicides and herbicides containing these amides BASF Aktiengesellschaft (DE) 1982-05-12 EP disclosed
EP-0049398-A1 4H-3,1-Benzoxazin derivatives, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1982-04-14 EP disclosed
EP-0046503-A1 Herbicidal agents on the the basis of cyclohexane-1,3-dione derivatives and 3,6-dichloro-2-picolinic-acid derivatives BASF Aktiengesellschaft (DE) 1982-03-03 EP disclosed
EP-0037925-A1 Substituted pyridazinones, process for their preparation, herbicides containing them and their use as herbicides BASF Aktiengesellschaft (DE) 1981-10-21 EP disclosed
EP-0035712-A1 N-aryl(thiol) carbamates, process for their preparation and their use in combating undesired plant growth BASF Aktiengesellschaft (DE) 1981-09-16 EP disclosed
EP-0032242-A1 4H-3,1-benzoxazine derivatives, process for their preparation and their use in inhibiting the growth of unwanted plants BASF Aktiengesellschaft (DE) 1981-07-22 EP disclosed