SCHEMBL10344971

SCHEMBL10344971

C=C(C)C(=O)Nc1ccccc1.CC(C)=C(C)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
RXFP1 Q9HBX9 1/20 0.49
NAPRT Q6XQN6 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MAPT P10636 3/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
GAA P10253 3/20 0.42
POLB P06746 2/20 0.42
GFER P55789 2/20 0.42
TAAR1 Q96RJ0 2/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
EPHX1 P07099 2/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9011492 0.90 KDM4E (0.58) KDM4EALDH1A1TDP1RXFP1NAPRT
SCHEMBL219147 0.86 KDM4E (0.66) KDM4EALDH1A1TDP1RXFP1NAPRT
SCHEMBL10600587 0.85 RXFP1 (0.48) KDM4EALDH1A1TDP1RXFP1NAPRT
SCHEMBL8641350 0.84 MAPT (0.59) KDM4EALDH1A1TDP1RXFP1NAPRT
Dimethylamine SCHEMBL10625504 0.83 KDM4E (0.61) KDM4EALDH1A1TDP1RXFP1NAPRT
Aniline SCHEMBL9418488 0.81 ALDH1A1 (0.56) KDM4EALDH1A1TDP1RXFP1NAPRT
Trimethylammonium SCHEMBL11436463 0.81 KDM4E (0.59) KDM4EALDH1A1TDP1RXFP1NAPRT
SCHEMBL166821 0.80 MAPT (0.67) KDM4EALDH1A1TDP1RXFP1NAPRT
SCHEMBL19501001 0.80 NPC1 (0.67) KDM4EALDH1A1TDP1RXFP1NAPRT
SCHEMBL13324799 0.79 NAPRT (0.61) ALDH1A1NAPRTHSD17B10MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0173584-B1 HEAT-DEVELOPABLE COLOR PHOTO-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1990-03-07 EP disclosed
US-4631251-A Heat-developable color photo-sensitive material with polymeric coupler KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-12-23 US disclosed
EP-0174177-A2 Heat-developable color photo-sensitive material KONICA CORPORATION (JP) 1986-03-12 EP disclosed
EP-0173584-A2 Heat-developable color photo-sensitive material KONICA CORPORATION (JP) 1986-03-05 EP disclosed