SCHEMBL10344995

SCHEMBL10344995

COCCN(C(=O)C(C)Cl)c1ccccc1C

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
ALDH1A1 P00352 3/20 0.42
CYP3A4 P08684 2/20 0.40
LMNA P02545 2/20 0.40
TRPM8 Q7Z2W7 1/20 0.40
KDM4E B2RXH2 1/20 0.39
HPGD P15428 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
ATM Q13315 2/20 0.38
GAA P10253 1/20 0.37
OXTR P30559 1/20 0.36
AVPR1A P37288 1/20 0.36
TSHR P16473 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10900094 0.90 TP53 (0.60) TP53MEN1KMT2AALDH1A1CYP3A4
SCHEMBL10895624 0.88 MEN1 (0.45) TP53MEN1KMT2AALDH1A1CYP3A4
SCHEMBL10527654 0.86 MEN1 (0.43) TP53MEN1KMT2AALDH1A1LMNA
SCHEMBL10945218 0.86 TP53 (0.45) TP53MEN1KMT2AALDH1A1CYP3A4
SCHEMBL10874180 0.85 TP53 (0.45) TP53MEN1KMT2AALDH1A1CYP3A4
SCHEMBL10896448 0.85 KMT2A (0.42) TP53MEN1KMT2AALDH1A1LMNA
SCHEMBL10898445 0.84 HPGD (0.42) TP53MEN1KMT2AALDH1A1KDM4E
SCHEMBL10899335 0.82 MEN1 (0.41) TP53MEN1KMT2AALDH1A1CYP3A4
SCHEMBL10896138 0.81 TP53 (0.43) TP53MEN1KMT2AALDH1A1CYP3A4
SCHEMBL10986800 0.81 TP53 (0.47) TP53MEN1KMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192111-B1 ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
EP-0121129-B1 2,5-DIHYDRO-5-ARYLIMINO-PYRROLES, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS HERBICIDES BASF Aktiengesellschaft (DE) 1989-02-01 EP disclosed
US-4789747-A BROAD LEAF PLANTS, GRASSES, WEEDS BASF AKTIENGESELLSCHAFT (DE) 1988-12-06 US disclosed
US-4761175-A M-anilido-urethanes and herbicides containing these compounds BASF AKTIENGESELLSCHAFT (DE) 1988-08-02 US disclosed
US-4744812-A HALOGENATED DIPHENYL ETHER BASF AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed
US-4726837-A Use of 4H-pyrido[2,3-d][1,3]oxazin-4-one derivatives for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1988-02-23 US disclosed
US-4715889-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
US-4692187-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
US-4632696-A POSTEMERGENCE, PREEMERGENCE APPLICATIONS BASF AKTIENGESELLSCHAFT (DE) 1986-12-30 US disclosed
EP-0192111-A1 Iso-ureas, processes for their production and their use as herbicides BASF Aktiengesellschaft (DE) 1986-08-27 EP disclosed
US-4225334-A USED WITH HERBICIDES CIBA-GEIGY CORPORATION (US) 1980-09-30 US disclosed
US-4220464-A Phenylglyoxylonitrile-2-oxime-cyanomethyl ether as plant growth regulator CIBA-GEIGY CORPORATION (US) 1980-09-02 US disclosed
US-4192827-A IN A DELAMINATED MATRIX OF A TRANSITITION METAL DICHALCOGENIDE CIBA-GEIGY CORPORATION (US) 1980-03-11 US disclosed
EP-0007588-A1 Tetrahydro-1,3-oxazines, herbicidal compositions containing acetanilides as herbicidal agents and said tetrahydro-1,3-oxazines as antagonistic agents, and their use for combating undesired plant growth BASF Aktiengesellschaft (DE) 1980-02-06 EP disclosed
US-4152137-A PREEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1979-05-01 US disclosed
US-4146387-A COMPRISING AN ALKYNYL-AMIDE AND A HALOACETANILIDE STAUFFER CHEMICAL COMPANY (US) 1979-03-27 US disclosed
US-4140516-A Encapsulation process employing phase transfer catalysts STAUFFER CHEMICAL COMPANY (US) 1979-02-20 US disclosed
US-4070389-A HERBICIDE ANTIDOTES CIBA-GEIGY CORPORATION (US) 1978-01-24 US disclosed
US-4059436-A Herbicidal compositions containing silylated chloroacetanilides CIBA-GEIGY CORPORATION (US) 1977-11-22 US disclosed
US-3996254-A Silylated chloroacetanilides for the regulation of plant growth CIBA-GEIGY CORPORATION (US) 1976-12-07 US disclosed